VCs see '400 club' as future (Silicon Valley / San Jose Business Journal)

"The median size of a U.S. venture fund in the first quarter of 2006 was $209 million, up from $77 million just four years ago, according to DowJones VentureOne, while 19 percent of the funds that closed in the quarter exceeded $500 million."

"Thirty percent of venture capital is now allocated to life sciences companies, up from about 10 percent at the height of the tech bubble, according to the National Venture Capital Association."